An instrument manipulates a treatment that it does not entirely control, but the instrument affects the outcome only indirectly through its manipulation of the treatment. The idealized prototype is ...
In the article that accompanies this editorial, Lu et al 5 conducted a systematic review on the use of instrumental variable (IV) methods in oncology comparative effectiveness research. The main ...
Instrumental variable (IV) methods for regression are well established. More recently, methods have been developed for statistical inference when the instruments are weakly correlated with the ...
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