Power analyses and sample size calculations are important parts of many research projects. Often, before data are even collected, it is necessary to calculate and justify the required sample size for ...

Significance testing, with appropriate multiple testing correction, is currently the most convenient method for summarizing the evidence for association between a disease and a genetic variant.

The procedure for allocating patients to a treatment arm in comparative clinical trials is frequently chosen with only minor deliberation. This decision may, however, ultimately impact the trial ...