Abstract: Multiple Sequence Alignment (MSA) is a fundamental challenge in bioinformatics, forming the basis for addressing numerous computational biology problems, e.g., protein structure prediction ...

pggb builds pangenome variation graphs from a set of input sequences. A pangenome variation graph is a kind of generic multiple sequence alignment. It lets us understand any kind of sequence variation ...

A command-line tool for detecting and extracting single homeologous polymorphisms (SHPs) from the subgenomes of allopolyploid species. This tool integrates three main algorithms, WGA, VCF2ALIGNMENT ...

ABSTRACT: Genomic surveillance has proven to be a critical source of information for understanding and responding to the COVID-19 pandemic. In Africa, genomic surveillance was very limited, and few ...

ABSTRACT: In North Carolina, candida infections are on the rise and pose a significant threat to human health in clinical settings. In addition, the rise of resistance to antifungal drugs has only ...

A team of scientists from the Singapore Centre for Environmental Life Sciences Engineering (SCELSE) and NTU School of Biological Sciences (SBS), has developed a new DNA sequence alignment algorithm ...

This study introduces MMPred, a software tool integrating epitope prediction and sequence alignment algorithms to simplify the setup of computational analyses aimed at the generation, investigation or ...